Desmethyl Celecoxib

CAS No. 170569-87-6

Desmethyl Celecoxib( —— )

Catalog No. M23766 CAS No. 170569-87-6

Demethyl celecoxib is a selective inhibitor of COX-2 with anti-inflammatory activity (IC50 of 32 nM).?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 37 In Stock
25MG 67 In Stock
50MG 113 In Stock
100MG 186 In Stock
200MG 279 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Desmethyl Celecoxib
  • Note
    Research use only, not for human use.
  • Brief Description
    Demethyl celecoxib is a selective inhibitor of COX-2 with anti-inflammatory activity (IC50 of 32 nM).?
  • Description
    Demethyl celecoxib is a selective inhibitor of COX-2 with anti-inflammatory activity (IC50 of 32 nM).?with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX-2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    170569-87-6
  • Formula Weight
    367.35
  • Molecular Formula
    C16H12F3N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:70 mg/mL (191 mM)
  • SMILES
    FC(F)(C1=NN(C(C2=CC=CC=C2)=C1)C3=CC=C(C=C3)S(=O)(N)=O)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Vinay Kumar Sthalam, et al. An Integrated Continuous Flow Micro-Total Ultrafast Process System (μ-TUFPS) for the Synthesis of Celecoxib and Other Cyclooxygenase Inhibitors. RETURN TO ISSUEPREVARTICLENEXT
molnova catalog
related products
  • Vinflunine Tartrate

    Vinflunine Tartrat is a new vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.

  • Hamaudol

    Hamaudol is a chromone isolated from Saposhnikovia divaricata,has analgesic and anti-inflammary activities, it showed inhibitory activity on COX-1 and COX-2 activities with values of 0.30, 0.57 mM, respectively.The CHCl3 extract of the root of Angelica japonica showed high inhibitory activity against human gastric adenocarcinoma (MK-1) cell growth.

  • Gaultherin

    Gaultherin has analgesic, and anti-inflammatory activities.Gaultherin lacks gastric ulcerogenic effect, because of it released salicylate in intestine slowly, not in stomach and it left the cyclooxygenase-1 unaffected, which was the source of cytoprotective prostaglandins in gastric epithelium.