Desmethyl Celecoxib
CAS No. 170569-87-6
Desmethyl Celecoxib( —— )
Catalog No. M23766 CAS No. 170569-87-6
Demethyl celecoxib is a selective inhibitor of COX-2 with anti-inflammatory activity (IC50 of 32 nM).?
Purity : >98% (HPLC)
Size | Price / USD | Stock | Quantity |
10MG | 37 | In Stock |
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25MG | 67 | In Stock |
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50MG | 113 | In Stock |
|
100MG | 186 | In Stock |
|
200MG | 279 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameDesmethyl Celecoxib
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NoteResearch use only, not for human use.
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Brief DescriptionDemethyl celecoxib is a selective inhibitor of COX-2 with anti-inflammatory activity (IC50 of 32 nM).?
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DescriptionDemethyl celecoxib is a selective inhibitor of COX-2 with anti-inflammatory activity (IC50 of 32 nM).?with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorCOX-2
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Research Area——
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Indication——
Chemical Information
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CAS Number170569-87-6
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Formula Weight367.35
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Molecular FormulaC16H12F3N3O2S
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Purity>98% (HPLC)
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SolubilityDMSO:70 mg/mL (191 mM)
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SMILESFC(F)(C1=NN(C(C2=CC=CC=C2)=C1)C3=CC=C(C=C3)S(=O)(N)=O)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Vinflunine Tartrate
Vinflunine Tartrat is a new vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.
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Hamaudol
Hamaudol is a chromone isolated from Saposhnikovia divaricata,has analgesic and anti-inflammary activities, it showed inhibitory activity on COX-1 and COX-2 activities with values of 0.30, 0.57 mM, respectively.The CHCl3 extract of the root of Angelica japonica showed high inhibitory activity against human gastric adenocarcinoma (MK-1) cell growth.
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Gaultherin
Gaultherin has analgesic, and anti-inflammatory activities.Gaultherin lacks gastric ulcerogenic effect, because of it released salicylate in intestine slowly, not in stomach and it left the cyclooxygenase-1 unaffected, which was the source of cytoprotective prostaglandins in gastric epithelium.